Bextra is a COX 2 drug manufactured by Pfizer. When Bextra was first released in 2001, Bextra packages included a warning about side effects such as stomach pain, diarrhea, heartburn, back pain, headache, nausea, and upper respiratory infection. In November 2002, Pfizer, upon the FDA’s orders, strengthened the Contraindications, Warnings, and Adverse Reactions sections Bextra’s prescribing information.
On April 7, 2005, Pfizer withdrew Bextra from the market at the FDA’s request. The FDA requested the withdrawal because of the incidence among Bextra users of heart attacks, strokes, and a potentially fatal skin condition called Stevens Johnson Syndrome.
On November 9, 2004, a study presented to the American Heart Association indicated that Bextra might carry a higher risk of fatal heart attacks, as much as two times, and cardiac problems than other COX 2 inhibitors. Bextra also appears to increase a patient’s risk of stroke. In light of this evidence, the FDA has strongly urged physicians to limit the number of prescriptions for Bextra and to consider Bextra alternatives when administering care.
Bextra has also been linked to Stevens Johnson Syndrome, toxic epidermal necrolysis and exfoliative dermatitis, as well as assorted allergic reactions. Stevens Johnson Syndrome and Toxic Epidermal Necrolysis (TEN) are two forms of the skin disease that can cause rash, skin peeling, and sores on the mucous membranes. Both Stevens Johnson Syndrome and Toxic Epidermal Necrolysis can be life threatening.
Stevens Johnson Syndrome is an immune-complex–mediated hypersensitivity disorder. Sufferers of Stevens Johnson Syndrome demonstrate a blistering of mucous membranes, typically in the mouth, eyes, and vagina, and patchy areas of rash. Sufferers of toxic epidermal necrolysis also experience a blistering of mucous membranes. In addition, the entire epidermis peels off in sheets from large areas of the body. Both Stevens Johnson Syndrome and Toxic Epidermal Necrolysis can be life threatening.
Showing posts with label Stevens Johnson Syndrome Lawyer. Show all posts
Showing posts with label Stevens Johnson Syndrome Lawyer. Show all posts
Friday, September 14, 2007
Stevens Johnson Syndrome Lawyer :: SJS Attorney
Stevens-Johnson Syndrome is a potentially deadly skin disease that usually results from a drug reaction. Another form of the disease is called Toxic Epidermal Necrolysis, and again this usually results from a drug-related reaction. Drugs that have been linked to Stevens-Johnson Syndrome include NSAIDS (non-steroid anti-inflammatory drugs), Allopurinol, Phenytoin, Carbamazepine, barbiturates, anticonvulsants, and sulfa antibiotics. In some cases, the condition is caused by a bacterial infection, and in many cases there is no known cause for the onset of Stevens-Johnson Syndrome or Toxic Epidermal Necrolysis.
These skin diseases can cause massive pain, suffering and anxiety. People that have taken or are taking medications such as the ones mentioned above are urged to familiarise themselves with the symptoms of SJS (Stevens-Johnson Syndrome) and Toxic Epidermal Necrolysis (TEN). This will enable you to seek immediate medical attention should the need arise, and early initiation of treatment can make a big difference to the seriousness of the disease as this can stop any secondary infections.
These skin diseases can cause massive pain, suffering and anxiety. People that have taken or are taking medications such as the ones mentioned above are urged to familiarise themselves with the symptoms of SJS (Stevens-Johnson Syndrome) and Toxic Epidermal Necrolysis (TEN). This will enable you to seek immediate medical attention should the need arise, and early initiation of treatment can make a big difference to the seriousness of the disease as this can stop any secondary infections.
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